Hello I have a 2008 Sienna and had to replace the keyless entry. I see a few are seeing the instructions work on the locks but not the sliding doors. I had the same problem and followed the instuctions again but before opening the door to lock in the setting I pressed both buttons for the sliding doors as well and heard it beep then I opened the drivers door and tested it out. It works fine now. I had looked everywhere online but could not find this answer. I hope it helps someone.
Mark