I think of Holleys as being a little easier to work on, but its not a big deal. The q-jets were fine carbs, when new or if properly rebuilt. The same thing will be true of the Holley. What I like about the Holleys is having the float bowl vent tube sticking up inside the air cleaner. When my motorhome sits for months - i just pour a few teaspoonfuls of fuel into the float bowl vent tube, pump the gas pedal twice, close the choke, and presto; the engine starts instantly.
I prefer manual chokes. If you use an automatic choke, the bimetallic 'clock spring' element that senses the engine heat should be a new replacement. The original bimetallic spring ages over the years, and no longer swings with temperature changes as much as it originally did.
If possible I would use a plastic spacer under the carb, to isolate it from the heat of the intake manifold. And dont overtighten the screws on the carburetor assembly!