If "tune ups" aren't done on a regular basis that usually means the car wasn't maintained. It all depends on what was done last. If not done regularly the car will run poorly or may not even run for that matter.
Oil / filter change
Trans fluid
Brake fluid
Brake service
Air filter
Distributor cap/rotor
Plug wires(possibly)
Spark plugs
Fuel filter
Timing belt/water pump/belts
Valve adjustment
Coolant