[INF3RN0666]

For the average consumer, NO. For commercial use, yes. Let's say your car is part of the police force. If it's a V6, the constant demand on the engine will be overwhelming. If you have a V8, the power is distributed amongst 8 cylinders, and you're less likely to have complete engine failure, but you also have more valves & springs that might need replacement at high mileage. As a general rule (not always true though), V8 deliver more power. More power means that you'll be red-lining the engine less often to accelerate at your desired rate. If you're driving a V6, you'll need to floor the gas further to get the same acceleration. So as you can see, you're placing more demand on a V6 compared to the V8 --> more failure rate. This also depends on the engineering of the engine (no doubt about it).