my friend did that in his car. it wasnt a honda but i imagine it would be about the same. there are two ways to do it i think.
1) the easiest way i think would be use some streetglow headlight or little accent neons as all u have to do is drill a hole to mount them. u can get to the driver side vent and the center vent by removing your guage cluster then follow the street glow instructions for mounting. the passenger side vent would be a little more difficult but im pretty sure u can get to it by takin out your glove box. i was gonna do this with little street glow headlight neons, one in the driver side vent, one in the center, and one in the passenger side.
2) if u want to use little lights or led's then most vent systems come in two pieces so u can remove the smaller piece of the vent system, mount the light and run the wires through the seam where the two pieces meet, hook it up to a power source and there ya go.
the street glow method would be easier but u would have to drill a hole in your vent, however neons arent prone to fading so u wouldnt have to worry about changing the bulbs, which as my friend could testify really sucks. in all the wiring isnt very difficult jus decide which method u want to do and go for it. hope that helped.