Silicone should help for now, but you'll probably have to keep applying it. There are probably other channels inside the door which could use a cleaning and lube if you havent done them allready. When your window is attempting to go up do you hear the motor working. Lots of regulators or motors I have replaced due to just being weak. There are so many different styles of window systems, you would have to be specific, there are plastic cable, metal cable, gear, direct linkage, hook ups from the motor to the window in many different cars.