96 Dodge Ram running rough

96 Dodge 1/2 ton pickup with a 318 and 120,000 miles. It is running rough and stalls off and on.. Does this warm or cold. Previously had a code reading 301 Cylinder misfire detected, but ran fine at that point. Since the problem has started it now reads 16 codes. P203 P202 P205 P207 P208 (Injector Circuit Open Cylinder 3, 2, 5, 7, 8.) P300 Random Multiple Cylinder Misfire Detected. 301 302 303 304 305 306 307 308 (Cylinder 1, 2, 3, 4, 5, 6, 7, 8 misfire detected) P0441 Emission Control System Purge Flow Fault. P0711 Trans Fluid temp Sensor A CKT Range Perf. I think the trans sensor is unrelated but the other 15 codes may have something in common. Does anyone know what would set them all off at once and cause the truck to run rough and stall?