2001 supercrew electrical problems

The coads that are comming up are Po113 Iat ckt high,P1289 cyl head temp high ,Po122 Tp snsr A ckt low input, Po453 EVAP pres snsr high, Po703 Brake sw input falt, P1702ckt inter fault, P0708 Trans range snsr ckt high,P0713 Trans fluid temp snsr high, P0135 Ho2 snsr heater fault po141 Ho2, P0141 Ho2, Po155 21, P1401 Dpfe ckt high. I have tracked it down to find out that none of these componets have a ground I am pretty sure that the gray-red signal return is the ground for most of these componets. If I ground this line everything starts working except for the Ho2 sensors and the brake swinput I have checked alot of things and something is draging this wire down so I unpluged everything and started ohming everything out all comes out fine but going to trans range all gears have .0000 from gray-red TR-1 TR-3 4x4 low indicator electronic pressure controll I am not understand the 4x4 indicator because my truck is 4x2 and should I be getting .oooo ohms from TR-1 and TR-3 can anyone help.:banghead: