85 Accleration Power Problem

My 85 2.5L 5 speed S-10 has a random problem with loosing power while I am on the highway. I notice that the truck is slowing down and when I accelaerate it does not provide any more power. When I let off on the accelaerator it dies and will not provide enough power to get out of first. If I let the truck site for a while it seems to clear up and works fine for an undeterminded time. I have a new fuel tank so I know I am not picking up any junk in the tank. Any suggestions on what could be the problem?

Change the INLINE FUEL FILTER on the frame rail. Should be right around the drivers door on the inside of the frame.