Dish Volume q's?

I am thinking about redoing my engine internals and I want to know if a higher comp ratio is better with: A heavier piston and a bigger dish volume or a smaller dish volume with a lighter piston? Both pistons are 10.5:1 comp ratio but I don't know why one would be better over the other. Any help would be greatly appreciated. Thinking JE Pistons high comp all motor 10.5:1. Thanks for any help you can give me!

10.5:1 isn't a high compression,12.1:1 is lol.One will rev better because it is lighter and puts less strain on the operation as a whole.