FFV/SEFI engine tuning

The engine in my '95 MPV is spec'd as a FFV/SEFI.
I understand the FFV to be Flexible Fuel Vehicle and the SEFI to be Sequential Electronic Fuel Injection.

Does anyone have experience tuning such an engine?
In hotrods, the SEFI seems to allow for performance enhancements. Is this somethign where a chip comes into play?
I don't want to dump a ton of money into a minivan but I am interested in exploring affordable alternatives to getting more performance.

Thanks,
db