2000 Sephia, no spark, no start

When I turn the key the starter runs, all electronics work, all the good stuff, but no spark to the plugs, therefore no start. Ideas on where to start??? Thanks!

Have you verified there is no spark, as it could be a fuel problem too? Also, you said the started runs... does the engine turn over?

are the cams turning? could be a broken belt
also if it is a spark problem check your fuses,
You should always start there