'49 Chevy -gonna turn into custom (engine and tranny)

I know this is not exactly a "muscle car" question, because it would be considered as a classic or custom car. However, I plan on purchasing a 1949 Chevrolet Convertible. I found it for a reasonable price, and the exterior and interior is in very good condition. However, these cars come with a 216 cubic-inch overhead-valve Six cylinder engine, and a 3 spd transmission.

I basically want this car to be really fast, have good 0-60, and good handling. However, i dont know much about classic cars, as because i drive a 69 vette..

My basic muscle car mentality would suggest dropping in a 454ci and a T-6 Richmond Trans. but i dont know if that would work..

If anyone has any knowledge on what i can do to improve performance and handling drastically on a car like that, it would be greatly appreciated.

Thanks...

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small block 350 polished, ported, balanced, and bored 30 over, with a built th 400 turbo trans