Silverado headers

I've seen a few opinions on this subject and I'm wondering what the latest is. I'm considering installing a set of JBA headers, either the ceramic coated or titanium. (2001 5.3 auto. ext.) I have a Borla cat-back dual exhaust, TrueFlow intake and Granatelli MAFS ........ No programming yet! Will the addition of headers reduce back-pressure too much?? I've seen some comments that this might be true.

I have a 2000 with a 5.3, Flo-Pro muffler and Granatelli MAF. I also have JBA silver coated shorty headers. The truck runs great. I don't know about Borlas but, I can't imagine that back-pressure would be a problem.