Who has experience with E85?

Hey, does anyone have any experience with E85? I'm trying to figure out if it would be something practical to consider for a "driver." I'd be using it in a RA III type 400ci with a Thermoquad and manual trans. What do I need to know?

Been my experience that it's not worth the money. For nearly the same capital investment (at least around here), it gets a third less mileage. It is pretty cool for Hi-Comp engines though.