OBD II Code reader not work on 09 E350

My trusty code reader which worked fine on my 96 E 150 gives a link error on my 09 E 350. Did they change the protocol? or do I have more wiring problems?

Problem solved, New reader reads fine. from what I read it looks like old reader may not be CAN compliant.

Check the OBD fuse will cause no communication at the DLC it may share the same fuse as the lighter or power port

Thank you, I think my old code reader is not CAN compliant. I went to autozone and had them plug in a code reader and it connected fine.