I got a 94 s10 4.3 cpi and latley i've putting gas in this thing every 5 min no feul smell or leaks but the gauge will be on 1/2 then e and once its hits e it dies out could it be the feul sender

How much are you putting in it?
What does it do with a full tank?
How much fuel does it take to fill it up after it says empty?

Oh its not much $10 in one trip of going about 20 miles max if too afraid to fill it up gas gauge floats if that helps

10$ worth does not take you very far at todays gas prices.
And will not raise a gas gauge over a hair.
If it is not leaking it is burning it.
How is the tune up end?

just did tune up new feul pressure regulator wires plugs cap and rotor i took a plug out yesterday and they look fine

Is the engine running rich or any black smoke out tail pipe?
You might want to recheck the fuel pressure and get it on a good engine capable scanner and see if any thing shows up.