What is the best spark plug and wire set to use and anything else i might need to replace on a complete tune up for a 2004 impala with a 3.4?

A C Delco.
I believe the wire set is part # 726UU and the plug 41-101.
You can use this link to find a retailer in your area that sells A C Delco parts:http://www.acdelco.com/index.jsp

Thank You.