Truck is missing and lights the SES. Code for 'misfire in cylinder #1' keeps reoccuring. Have replaced coil on #1, all plugs and all plug wires. Any thoughts?

Truck is missing and lights the SES. Code for 'misfire in cylinder #1' keeps reoccuring. Have replaced coil on #1, all plugs and all plug wires. Any thoughts?

What engine and mileage?
Does it have good hot blue spark to plug?
Double check spark plug or switch with another one?
Got compression?
Check injector plug in wiring and for injector pulse.

5.3L with 44,000 miles. Plug looked good, but have yet to check spark. Carbon build up in throttle body?

5.3L with 44,000 miles. Plug looked good, but have yet to check spark. Carbon build up in throttle body?

Check for good spark and switch plug and or coil /wire with another one and see if miss moves to another cylinder.

Good spark, had codes erased, didn't make it out of parking lot before SES came back on. How can a shade tree check injector?

Good spark, had codes erased, didn't make it out of parking lot before SES came back on. How can a shade tree check injector?

If good spark and plug good and good compression.
First check on a injector would for injector pulse with a injector noid light.
If good injector pulse the best shade tree is to test switch injector with another cylinder and see if miss follows injector.

Thanks MT, I'll give it a shot!

Thanks MT, I'll give it a shot!
Good luck and let us know how it goes.
PS
I have found some where the coil and or injector plug in was not making good connection. Try unplugging and plugging them back on to.

#1 injector replaced (by a pro) and problem seems to be fixed at higher revs, but still idles poorly. He thinks poor idle is due to the bottle of injector cleaner clogging fuel filter? Will change the fuel filter. Are we into vacuum leaks? Yikes!

#1 injector replaced (by a pro) and problem seems to be fixed at higher revs, but still idles poorly. He thinks poor idle is due to the bottle of injector cleaner clogging fuel filter? Will change the fuel filter. Are we into vacuum leaks? Yikes!

Good luck.
Also check egr valve if a bad idle.
Good luck and let us know how it goes.