No fire to plugs 1 and 4. Replaced appropriate coil but still not firing those two plugs.
Coil posts are clean/no visible contamination. Replaced plug wires also.
Anybody have any ideas?

Did you replace the Ignition Module that the coils sit on?? That'd be my next step. (It's a 3.8 right??)

Thanks, it is a 3.1, but the coils do sit on an ignition module.
Is there a test for the module?

There's no way for you to test it. If there's an AutoZone nearby, they can test them for free.

Problem did turn out to be the ignition control module.
Running great now, only had to tweak up the idle a little.
Thanks for the dead-on help.